National Living Donor Kidney Sharing Scheme
Since January 2012, the National Living Donor Kidney Sharing Schemes (NLDKSS) is the collective term used to describe the schemes
in which donated kidneys are 'shared' across the UK. The NLDKSS include a number of developments to the original paired/pooled
donation (PPD) and non-directed altruistic donation (NDAD) schemes which were established in 2007 after the introduction of the
Human Tissue Act 2004 and the Human Tissue (Scotland) Act 2006 in September 2006. The NLDKSS include:
Paired/pooled donation (PPD) - donor-recipient pairs who are incompatible by Human Lymphocyte Antigen (HLA) type or ABO blood group and unable to donate directly, one to the other, are registered in a national scheme to achieve compatible transplants with other pairs. When two pairs are involved it is called 'paired' donation; more than two pairs is called 'pooled' donation. Compatible donor-recipient pairs who seek a better HLA or age match may also be registered in the scheme.
Non-directed altruistic donation (NDAD) - a person donates to a recipient on the national transplant list whom they have never met or previously heard about.
Altruistic Donor Chains (ADC) - a NDAD chooses to donate into the paired/pooled scheme to create a chain of transplants. The donated kidney is allocated to a recipient in the paired/pooled scheme and, in turn, the donor registered with that recipient donates to another recipient and so on. The chain ends when the last donor donates to a recipient on the national transplant list.
Living Donor Kidney Matching Runs (LDKMR) are performed 4 times per year to identify paired/pooled exchanges and altruistic donor chains in optimal combinations (LDKMR matching process).